Thuy Le, MD, D.Phil



Oxford University Clinical Research Unit

Thuy Le, MD, D.Phil

Associate Professor of Medicine
Associate Professor of Molecular Genetics and Microbiology
Affiliate, Duke Global Health Institute

Dr. Thuy Le is an Associate Professor of Medicine, Associate Professor of Molecular Genetics and Microbiology at Duke, and an affiliate at the Duke Global Health Institute. She is a Co-Director of the Clinical Core of the Duke Center for AIDS Research and a Co-Director of the NIH-sponsored Tropical Medicine Research Center for Talaromycosis in Vietnam.

Dr. Le leads an international research program based in Vietnam focusing on developing novel diagnostic and therapeutic strategies for talaromycosis, a severe HIV-associated fungal infection endemic in Southeast Asia. She has wet labs both at Duke and in Vietnam which focus on pre-clinical development of novel non-culture based diagnostics and in vitro and in vivo testing of novel therapeutics. She led the first-ever multi-center clinical trial that has defined international treatment guidelines for talaromycosis, and currently leads multiple NIH grants to advance a pipeline of novel non-culture diagnostics for talaromycosis. Her passion in the translation of knowledge and technologies into real-world disease control and prevention strategies has placed her at the forefront of national and international leadership in the fields of HIV and Mycology. Dr. Le is a member of multiple WHO Guidelines Committees on HIV Therapy, Management of Advanced HIV Disease, and Management of AIDS-associated Cryptococcal Meningitis and Histoplasmosis. She leads the European Confederation of Medical Mycology Guidelines for Endemic Mycoses and leads the talaromycosis section of the NIH/CDC/HIVMA/IDSA Guidelines on Opportunistic Infections. Dr. Le is a new faculty and research mentor at HYC but has extensive experience providing research mentorship to medical and non-medical trainees at all levels of training both at Duke and overseas in Southeast Asia.