Dr. Thuy Le is an Associate Professor of Medicine, Associate Professor of Molecular Genetics and Microbiology at Duke, and an affiliate at the Duke Global Health Institute. She is a Co-Director of the Clinical Core of the Duke Center for AIDS Research and a Co-Director of the NIH-sponsored Tropical Medicine Research Center for Talaromycosis in Vietnam.

Dr. Le leads an international research program based in Vietnam focusing on developing novel diagnostic and therapeutic strategies for talaromycosis, a severe HIV-associated fungal infection endemic in Southeast Asia. She has wet labs both at Duke and in Vietnam which focus on pre-clinical development of novel non-culture based diagnostics and in vitro and in vivo testing of novel therapeutics. She led the first-ever multi-center clinical trial that has defined international treatment guidelines for talaromycosis, and currently leads multiple NIH grants to advance a pipeline of novel non-culture diagnostics for talaromycosis. Her passion in the translation of knowledge and technologies into real-world disease control and prevention strategies has placed her at the forefront of national and international leadership in the fields of HIV and Mycology. Dr. Le is a member of multiple WHO Guidelines Committees on HIV Therapy, Management of Advanced HIV Disease, and Management of AIDS-associated Cryptococcal Meningitis and Histoplasmosis. She leads the European Confederation of Medical Mycology Guidelines for Endemic Mycoses and leads the talaromycosis section of the NIH/CDC/HIVMA/IDSA Guidelines on Opportunistic Infections. Dr. Le is a new faculty and research mentor at HYC but has extensive experience providing research mentorship to medical and non-medical trainees at all levels of training both at Duke and overseas in Southeast Asia.