Residents and Fellows


Moshi, Tanzania

Kilimanjaro Christian Medical Centre

Holly Biggs, MD, MPH

Global Health Pathway Graduate

Internal Medicine
Department of Medicine


Dr. Holly Biggs graduated from the Global Health Pathway as an Internal Medicine resident in 2010 and is currently a medical epidemiologist at CDC. After graduating from the Global Health Pathway, she completed Infectious Diseases Fellowship at Duke University Medical Center then was a CDC Epidemic Intelligence Service Officer. Dr. Biggs received her undergraduate degree in Biological Sciences from the University of Illinois at Chicago and her MD from the University of Illinois College of Medicine.

As a Global Health resident, she completed a Master’s in Public Health with a Certificate in Global Health at the University of North Carolina at Chapel Hill and then spent nine months in Moshi, Tanzania where her time was divided between clinical work and research at Kilimanjaro Christian Medical Center (KCMC).  Her research involved evaluating leptospirosis as a cause of febrile illness in hospitalized patients and found that leptospirosis is likely endemic in the area. During this research project she worked with her GHRF mentor, Dr John A Crump, the KCMC-Duke Collaboration, and collaborators at US Centers for Disease Control and Prevention. Dr. Biggs continued work with Dr. Crump and the KCMC-Duke Collaboration during her Infectious Diseases Fellowship, and spent an additional 2 years in Moshi, Tanzania working on acute febrile illness and bacterial zoonoses research in follow up to the work she did as a global health resident. 

Representative Publications:

  • Allan KJ, Biggs HM, Halliday JEB, Kazwala RR, Maro VP, Cleaveland S, Crump JA. Epidemiology of Leptospirosis in Africa: A Systematic Review of a Neglected Zoonosis and a Paradigm for ‘One Health’ in Africa. PLoS Negl. Trop. Dis.2015;9(9).
  • Moon AM, Biggs HM, Rubach MP, Crump JA, Maro VP, Saganda W, Reddy EA. Evaluation of in-Hospital Management for Febrile Illness in Northern Tanzania before and after 2010 World Health Organization Guidelines for the Treatment of Malaria. PloS one. 2014;9(2).
  • Biggs HM, Lester R, Nadjm B, Mtove G, Todd JE, Kinabo GD, Philemon R, Amos B, Morrissey AB, Reyburn H, et al. Invasive Salmonella Infections in Areas of High and Low Malaria Transmission Intensity in Tanzania. Clin. Infect. Dis.2014;58(5):638-647.
  • Biggs HM, Hertz JT, Munishi OM, Galloway RL, Marks F, Saganda W, Maro VP, Crump JA. Estimating leptospirosis incidence using hospital-based surveillance and a population-based health care utilization survey in Tanzania. PLoS Negl Trop Dis. 2013 Dec 5;7(12):e2589. doi: 10.1371/journal.pntd.0002589. eCollection 2013.
  • Biggs HM, Galloway RL, Bui DM, Morrissey AB, Maro VP, Crump JA. Leptospirosis and human immunodeficiency virus co-infection among febrile inpatients in northern Tanzania. Vector Borne Zoonotic Dis. 2013 Aug;13(8):572-80. doi: 10.1089/vbz.2012.1205. Epub 2013 May 10.
  • Bouley AJ, Biggs HM, Stoddard RA, Morrissey AB, Bartlett JA, Afwamba IA, Maro VP, Kinabo GD, Saganda W, Cleaveland S, Crump JA. Brucellosis among hospitalized febrile patients in northern Tanzania. Am J Trop Med Hyg. 2012 Dec;87(6):1105-11. doi: 10.4269/ajtmh.2012.12-0327. Epub 2012 Oct 22.
  • Biggs HM, Bui DM, Galloway RL, Stoddard RA, Shadomv SV, Morrissev AB, Bartlett JA, Onvango JJ, Maro VP, Kinabo GD, Saganda W, Crump JA. Leptospororis among hospitalized febrille patients in northern Tanzania. Am J Trop Med Hyg  2011 Aug; 85(2):275-81.